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Deanship of Scientific Research
Document Details
Document Type
:
Project
Document Title
:
Development of multi-resistance status in the cells of bacteria Salbeh gram.
تطور صفة المقاومة المتعددة في الخلايا البكتيرية سالبية الجرام.
Document Language
:
Arabic
Abstract
:
In this study, mutations were separated isolates of Pseudomonas aeruginosa and Claibciella pneumoniae and Antirubaktr Aarogyinz and Protais Fogars using the center contains high concentrations of a compound Sbrovluxasin. By studying the sensitivity of these mutations to different types of antimicrobials compared to the original isolation, the results showed that all the mutations isolated, with the exception Alotfrtin PaM3 and PvM1, characterized by resistance to multiple different types of antimicrobials. As for the Tafrtin PaM3 and PvM1 Vtaatmazan Bmquaomthma only to vehicles used fluoroquinolones. When examining the amount of a compound norfloxacin taken within the cells of mutations and isolates the original results demonstrated that there is low (2.1 to 3.8 times) in the amount of a compound norfloxacin taken within the cells of mutations multi-resistance compared Baezzlat original, but there is no change in the amount of norfloxacin taken within Alotfrtin PaM3 and PvM1. The observed increase in the amount of a compound norfloxacin taken only within the cells of a leap when you add PaM2 compound carbonyl cyanide m-chlorophenylhydrazone Mellimul concentration of 0.25, but did not show any changes on the other mutations. By studying the protein components of the outer membrane of the bio-Separated mutations and isolation of origin, the results showed changes in the amount of proteins in the outer membranes of all multi-resistance mutations compared with isolation of origin. But there is no change in the Alotfrtin PaM3 and PvM1. I have been studying the effect of some compounds on the sensitivity of mutations isolated and isolates indigenous to different types of antimicrobials, and the results showed that the vehicles Rzerben and verapamil, and nicardipine had no effect on all mutations, or isolates the original with the exception of the boom PaM2, where more of these compounds of the sensitivity of the mutation to all antimicrobials tested . For Tntrbat Alpolemeksin b Ninibeptad Spirmaidin and spermine and increase understanding of the sensitivity of all mutations, or the original isolates of different types of antibiotics used. The results also demonstrated that the compound salicylate reduces the sensitivity of microbes to antibiotics used.
Publishing Year
:
1426 AH
2006 AD
Sponsor Name
:
kau
Sponsorship Year
:
1426 AH
2006 AD
Added Date
:
Wednesday, April 30, 2008
Researchers
Researcher Name (Arabic)
Researcher Name (English)
Researcher Type
Dr Grade
Email
سليمان محمد الأنصاري
alansari, soliman mohammed
Investigator
Doctorate
Files
File Name
Type
Description
30704.docx
docx
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